Annexus Health Unifies Patient Financial Assistance with Connected, End-to-End Platform

Built on AssistPoint®, the Annexus Platform connects patient assessment and enrollment, claims management, and ongoing funding management to help patients start treatment sooner and enable healthcare providers to improve reimbursement performance

CRANBERRY TOWNSHIP, Pa., Nov. 10, 2026 — Annexus Health today announced the launch of the Annexus Platform, designed to help healthcare providers identify, secure, and manage patient financial assistance throughout treatment. Built on the proven foundation of the AssistPoint software, the Platform uses AI and automation within existing provider workflows to match patients with assistance opportunities, enroll patients in financial assistance programs, manage claims, and maintain funding across the course of care.

Provider organizations can manage the Platform using their own teams, share workflow execution with Annexus, or outsource financial assistance operations through Annexus Managed Services. The Platform works alongside existing provider systems and requires no upfront capital investment.

Financial toxicity, or the financial distress caused by medical costs, can put needed treatment out of reach, especially in specialty care. Even with health insurance, patients with cancer can face out-of-pocket costs that disrupt access to care, according to the National Cancer Institute.

Financial assistance can help, but provider teams often manage program requirements, applications, claims, and renewals through a patchwork of spreadsheets, manual processes, and separate program portals. That fragmented administrative work leaves less time to help patients understand their options and secure support before costs become a barrier to care. Assistance efforts can also be reactive, beginning only when a patient asks for help. As a result, eligible patients can be overlooked and available funding can go unused. Delays in assistance can affect treatment starts and adherence, while unresolved claims can delay provider reimbursement.

Founded in 2017, Annexus pioneered software-as-a-service technology to connect provider workflows with financial assistance programs. As its network expanded beyond community oncology into infusion centers, specialty pharmacies, home infusion, and health systems, the company added operational services to support provider needs. The Platform and Annexus Managed Services build on that experience to help organizations manage the full financial assistance lifecycle at scale.

"Since partnering with Annexus Health, we've seen a significant evolution in how we support patients and manage financial assistance," said Dr. Jeff Vacirca, CEO of New York Cancer & Blood Specialists. "The Annexus Platform helps us connect patients to manufacturer co-pay assistance and foundation funding, and with Annexus Managed Services, we've been able to extend that impact even further by strengthening our revenue cycle processes and achieving outcomes we hadn't thought possible."

Three Connected Workflows
The Platform brings treatment orders, assistance applications, claims, and funding information together across provider systems, including electronic health record, practice management, billing, infusion, and pharmacy systems. This connection supports three core workflows:

• Initial Patient Assessment: Automatically screens every treatment order and uses AI to help match patients with thousands of financial assistance opportunities, including all manufacturer co-pay programs and charitable foundation programs across high-cost specialty therapeutics. The Platform advances likely matches through an organized enrollment processing workflow, helping teams manage applications and track status and outcomes.
• Claims Management: Uses automation and AI-supported matching to review medical benefit claims from provider systems and identify those that may qualify for reimbursement through assistance programs. The Platform then helps teams prepare, submit, track, and resolve eligible claims, with final documentation returned to the provider's billing system.
• Ongoing Patient Management: Monitors assistance throughout treatment, including award balances and expiration dates. It alerts teams when funds run low, keeps assistance information accurate through reconciliation, maintains a watchlist for patients awaiting available funding, and supports re-enrollment.

For providers, these workflows help teams identify assistance earlier, reduce administrative work, and maintain funding throughout treatment while helping improve financial assistance collections and reimbursement performance.

Connecting Life Sciences Programs with Provider Workflows
For life sciences organizations, the Platform extends patient support programs into provider workflows where financial assistance is managed and works alongside existing hub and patient access infrastructure. When connectivity with a program is enabled, relevant enrollment, claims, and ongoing funding activity can be exchanged with the Platform, helping keep information synchronized across systems. Annexus' dedicated life sciences team works with manufacturers to extend that connectivity across their brand portfolios.

"Patients should not have to know which assistance programs exist or when to ask for help," said Brad Frazier, CEO and co-founder of Annexus Health. "Our goal is to help providers identify that support earlier and manage it throughout treatment. By connecting assessment, enrollment, claims management, and ongoing funding management, the Platform takes on much of the administrative work, giving teams more time to focus on and interact with patients. That can help with faster treatment starts and reduced financial toxicity while improving reimbursement performance for providers."

Real-World Results Across the Annexus Network
Annexus has helped secure more than $11 billion in financial assistance for more than 400,000 patients. Its provider network spans more than 735 healthcare organizations, 32,000 sites of care, and 124,000 treating providers. Measured results include:

• 5.2-day reduction in time to treatment, on average
• 75% increase in financial assistance collections, on average*
• 55% lower cost per dollar of financial assistance collected, on average*
• 78% reduction in days to payment on digitally integrated claims, from 19.5 days to 4.3 days

*Based on pre- and post-implementation comparisons among representative provider clients.

Annexus maintains HITRUST r2 Certification, an independent validation of its information security program.

Annexus will showcase the Platform at booth P10 during McKesson Accelerate, Nov. 16-18, at Wynn Las Vegas. For more information, visit annexushealth.com.

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SOURCE Annexus Health